Regular cleaning will extend the life of your mattress, especially if you sleep in direct contact with its surface.
Do not put your mattress in the washing machine. Cleaning with a hose or in a bathtub is best. Do not forget to close the valve while washing. For general cleaning, a quick scrubbing with Formula 409®, BioClean™ All-Purpose Cleaner, or other general household cleaner is best.
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For tree sap, spot clean with a cotton rag soaked in rubbing alcohol. This will take some work and sap will likely leave a stain. However, a dusting with talc or baby powder when you are done should eliminate any residual stickiness.